What is a thermal cycler used for?

A thermal cycler, also known as a PCR machine, is a laboratory instrument used to amplify DNA fragments through the polymerase chain reaction (PCR) process. This powerful tool is essential for molecular biology and genetics research as well as medical diagnosis and forensic analysis.

Thermal cyclers work by cycling through a series of temperature changes to facilitate the PCR process. Key components of a thermal cycler include a heating block that allows rapid temperature changes and a thermal lid that ensures even heat distribution in the sample. The machine can precisely control the temperature of the reaction mixture to achieve the denaturation, annealing and extension steps of PCR.

Beijing LIUYI PCR Machine

So, what is a thermal cycler used for? The main purpose of a thermal cycler is to amplify specific DNA sequences. This is accomplished by repeatedly heating and cooling the reaction mixture to denature the DNA, anneal it with primers, and then extend it with DNA polymerase. Therefore, only a few initial copies are needed to generate millions of copies of the target DNA sequence.

In research, thermal cyclers are used to study gene expression, genetic variation and DNA sequencing. It is also used for cloning, mutagenesis and gene functional analysis. In medical diagnostics, thermal cyclers are used to detect infectious disease, genetic disease, and cancer biomarkers. Additionally, in forensic science, these instruments are critical for DNA analysis and identifying individuals from biological evidence.

The versatility and precision of thermal cyclers have revolutionized the field of molecular biology, allowing scientists to explore and understand the genetic basis of life and disease. The technology has also played a key role in the development of personalized medicine and has had a significant impact on various industries including healthcare, agriculture and environmental sciences.

In summary, thermal cyclers are an indispensable tool for DNA amplification and are widely used in scientific research, medicine, and forensic analysis. Its ability to copy DNA sequences quickly and accurately makes it a valuable asset in improving our understanding of genetics and its practical applications in different fields.

Beijing Liuyi Biotechnology Co. Ltd (Liuyi Biotechnology) has specialized in manufacturing electrophoresis instruments for more than 50 years with our own professional technical team and R&D center. We have reliable and complete production line from design to inspection, and warehouse, as well as marketing support. Our main products are Electrophoresis Cell (tank/chamber), Electrophoresis Power Supply, Blue LED Transilluminator, UV Transilluminator, Gel Image & Analysis System etc. We also supply the lab instruments like PCR instrument, vortex mixer and centrifuge for laboratory.

If you have any purchasing plan for our products, please don’t hesitate to contact us. You can send us message at email [email protected] or [email protected], or please call us at +86 15810650221 or add Whatsapp +86 15810650221, or Wechat: 15810650221.

Please Scan the QR code to add on Whatsapp or WeChat.