GEN Cutting Edge News
The news recently reported from the GEN (Genetic Engineering & Biotechnology News) said that the U.K. authorities have granted approval to Casgevy, the CRISPR-Cas9 therapy formerly known as exa-cel developed by Vertex Pharmaceuticals and CRISPR Therapeutics. It is a a landmark announcement for the CRISPR field and the sickle cell disease (SCD) community.he U.S. Food and Drug Administration (FDA) is expected to follow suit in the next three weeks, having issued a decision date of December 8. A further decision on Bluebird bio’s related SCD therapy should come later that month. The U.K. approval was announced by the Medicines and Healthcare products Regulatory agency. The CRISPR-Cas9 technology will offer a cure or more effective treatments for sickle cell disease.
Picture from website of Genetic Engineering & Biotechnology News
Knowledge About Sickle Cell Disease (SCD)
Sickle cell disease (SCD), also known as sickle cell anemia, is a genetic disorder that affects red blood cells. It is an inherited condition caused by a mutation in the HBB gene, which encodes a component of hemoglobin, the protein in red blood cells responsible for carrying oxygen throughout the body. This mutation leads to the production of abnormal hemoglobin known as hemoglobin S (HbS).
In individuals with sickle cell disease, the abnormal hemoglobin causes red blood cells to become rigid, sticky, and crescent-shaped (resembling a sickle). These abnormal cells can get stuck in small blood vessels, leading to various complications, including pain, anemia, organ damage, and a higher risk of infections.
Easy Way For Diagnosing Sickle Cell Disease
Beijing Liuyi Biotechnology Co. Ltd (Liuyi Biotechnology) has specialized in manufacturing electrophoresis instruments for more than 50 years with our own professional technical team and R&D center. We have reliable and complete production line from design to inspection, and warehouse, as well as marketing support. Our main products are Electrophoresis Cell (tank/chamber), Electrophoresis Power Supply, Blue LED Transilluminator, UV Transilluminator, Gel Image & Analysis System etc.
Liuyi Bilotechnology manufactures one model of electrophoresis tank called cellulose acetate membrane elctrophoresis tank DYCP-38C which can be adapted for the analysis of hemoglobin variants, including those associated with sickle cell disease (SCD). It is a traditional and economic method for hemoglobin electrophoresis.
If you are interested in this simple and economic electrophoresis method, please visit the following article for protocols and guidelines of hemoglobin electrophoresis offered by our experimenters.
Experiment for separating serum protein by Cellulose Acetate Membrane Electrophoresis
The Beijing Liuyi biotechnology have been focus on manufacturing electrophoresis products for more than 50-year history in China and the company can provide stable and high-quality products all around the world. Through years of development, it is worthy of your choice!
We are now looking for partners, both OEM electrophoresis tank and distributors are welcomed.
If you have any purchasing plan for our products, please don’t hesitate to contact us. You can send us message at email [email protected] or [email protected], or please call us at +86 15810650221 or add Whatsapp +86 15810650221, or Wechat: 15810650221.
Please Scan the QR code to add on Whatsapp or WeChat.
References
Post time: Nov-21-2023